By the time of the outbreak of World War I the glory days of Amedee were relegated to the past. A major turning point happened in 1916 when the hotel was acquired by the McKissick Cattle Company, which was more interested with acreage of surrounding Amedee, than the hotel.
Unlike previous owners, the McKissick Cattle Company, leased the hotel. Visitors to Amedee dwindled due to many circumstances from the depopulation of the east side of Honey Lake Valley from World War I to the NCO Railroad that abandoned its line that gave Amedee its original lifeblood. In 1925, a major event occurred with the McKissick Cattle Company and James Humphrey became the sole proprietor of the Amedee Hotel. Humphrey hired caretakers, and on occasion still provided accommodations. By the mid-1930s, the building was abandoned. In the spring of 1950, Jim Humphrey’s son, Jack, dismantled the hotel. He hauled the lumber across a dry Honey Lake bed to his home at Milford. It was his intention to use it in the construction of a new home. However, that summer, the lumber which was stored in a barn, was destroyed when a forest fire ravaged the area behind Milford.
